Detection of breast cancer microcalcifications using a dual-modality SPECT/NIR fluorescent probe
使用双模 SPECT/NIR 荧光探针检测乳腺癌微钙化
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作者：Kumar R Bhushan, Preeti Misra, Fangbing Liu, Sanjeev Mathur, Robert E Lenkinski, John V Frangioni
Abstract
Efficient chemical synthesis of a trifunctional, hydroxyapatite-binding molecule, which provides simultaneous in vivo imaging by NIR fluorescence and SPECT/CT has been described. Quantitation by SPECT provides the "gold standard" by which NIR fluorescence tomography of breast cancer microcalcifications can now be compared and optimized.
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