Sonchus asper (L.) Hill extracts: phytochemical characterization and exploitation of its biological activities by loading into nanoformulation

苦苣提取物:植物化学表征及通过纳米制剂开发其生物活性

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作者:Valentina Parisi #, Valentina Santoro #, Immacolata Faraone #, Nadia Benedetto, Antonio Vassallo, Nunziatina De Tommasi, Luigi Milella, Antonio Nesticò, Gabriella Maselli, Anna Maria Fadda, Carla Caddeo

Discussion

The commercialization of S. asper could: (i) contribute to improving the well-being of rural and urban communities, being S. asper a wild edible plant available at low cost, environmentally friendly, resilient, and adaptable; (ii) generate landowner economic returns.

Methods

Liquid chromatography-mass spectrometry analyses were conducted to characterize the metabolite profile of the raw and cooked leaf extracts, and the extract from discarded leaves. The antioxidant activity, the hypoglycaemic effect and the incorporation into liposomes were evaluated.

Results

38 compounds and 6 essential amino acids were identified. The incorporation into liposomes maximized the health-promoting properties for potential pharmaceutical or food applications.

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