Abstract
PURPOSE: Catheters and guidewires are used extensively in cardiac catheterization procedures such as heart arrhythmia treatment (ablation), angioplasty, and congenital heart disease treatment. Detecting their positions in fluoroscopic X-ray images is important for several clinical applications, for example, motion compensation, coregistration between 2D and 3D imaging modalities, and 3D object reconstruction. METHODS: For the generalized framework, a multiscale vessel enhancement filter is first used to enhance the visibility of wire-like structures in the X-ray images. After applying adaptive binarization method, the centerlines of wire-like objects were extracted. Finally, the catheters and guidewires were detected as a smooth path which is reconstructed from centerlines of target wire-like objects. In order to classify electrode catheters which are mainly used in electrophysiology procedures, additional steps were proposed. First, a blob detection method, which is embedded in vessel enhancement filter with no additional computational cost, localizes electrode positions on catheters. Then the type of electrode catheters can be recognized by detecting the number of electrodes and also the shape created by a series of electrodes. Furthermore, for detecting guiding catheters or guidewires, a localized machine learning algorithm is added into the framework to distinguish between target wire objects and other wire-like artifacts. The proposed framework were tested on total 10,624 images which are from 102 image sequences acquired from 63 clinical cases. RESULTS: Detection errors for the coronary sinus (CS) catheter, lasso catheter ring and lasso catheter body are 0.56 ± 0.28 mm, 0.64 ± 0.36 mm, and 0.66 ± 0.32 mm, respectively, as well as success rates of 91.4%, 86.3%, and 84.8% were achieved. Detection errors for guidewires and guiding catheters are 0.62 ± 0.48 mm and success rates are 83.5%. CONCLUSION: The proposed computational framework do not require any user interaction or prior models and it can detect multiple catheters or guidewires simultaneously and in real-time. The accuracy of the proposed framework is sub-mm and the methods are robust toward low-dose X-ray fluoroscopic images, which are mainly used during procedures to maintain low radiation dose.