Set-up and pilot of a population cohort for the study of the natural history of COPD and OSA: the PULSAIB study

建立和试点人群队列,用于研究慢性阻塞性肺疾病和阻塞性睡眠呼吸暂停的自然史:PULSAIB 研究

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Abstract

AIMS: We describe the set-up of a population-based study focussed on respiratory conditions, and describe a pilot study - the PULmons SAns Illes Balears (PULSAIB) study - aimed at investigating the natural history of COPD, obstructive sleep apnoea (OSA), and other common chronic diseases. METHODS: A cross-sectional study was designed to survey two fieldwork areas, one rural and one urban, in the Balearic Islands, Spain. Tests conducted included a questionnaire, spirometry with post-bronchodilator (PBD) test, and portable respiratory polygraphy. RESULTS: We assessed all processes and tools to be used, and piloted them in 175 participants from Bunyola (rural) and 130 participants from the Son Pizà area (urban). Within this first cross-sectional assessment of the Balearic population aged 30 to 80 years, we report the prevalence of airflow limitation defined as a PBD FEV1/FVC ratio <0.7 and the prevalence of OSA defined as an apnoea-hypopnoea index (AHI) >10/hour. CONCLUSION: A cohort study in the Balearic population to investigate the natural history of COPD and OSA is feasible.

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