From mouse to man: predicting biased effects of beta-blockers in asthma

从小鼠到人类:预测β受体阻滞剂在哮喘治疗中的偏倚效应

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Abstract

This article is a Commentary on Thanawala VJ, Valdez DJ, Joshi R, Forkuo GS, Parra S, Knoll BJ, Bouvier M, Leff P and Bond RA (2015). Beta‐blockers have differential effects on the murine asthma phenotype. Br J Pharmacol 172: 4833–4846. doi: 10.1111/bph.13253. The authors reply in Bond RA (2016). Differences in asthma study models and the effectiveness of β(2)‐adrenoceptor ligands: response to Lipworth et al. Br J Pharmacol 173: 250–251. doi: 10.1111/bph.13334.

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