Abstract
A 30-year-old Japanese man who traveled to the Republic of Ghana was diagnosed with falciparum malaria while undergoing chemotherapy for acute leukemia in Japan. We considered him to be at high risk of severe disease; however, he showed no signs of severe malaria and was treated with 3 days of oral artemether/lumefantrine. The patient's medical history may have contributed to the suppression and successful treatment of falciparum malaria without severe complications.