External Nasal Reconstruction in Patients With Extranodal Natural Killer (NK)/T-cell Lymphoma, Nasal Type

鼻外自然杀伤 (NK)/T 细胞淋巴瘤患者的鼻外重建术(鼻型)

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Abstract

Extranodal NK/T-cell lymphoma, nasal type (ENKTL-NT), is a rare and aggressive lymphoma of NK or T-cell origin, characterized by necrotizing and destructive granulomatous lesions that primarily affect facial midline structures. In the head and neck region, it often leads to extensive destruction of soft tissue, bone, and cartilage, potentially resulting in external nasal deformity and necrosis. This study reports on nasal reconstruction and its clinical course in patients with ENKTL-NT. Two patients with ENKTL-NT, who achieved remission following chemoradiotherapy, underwent external nasal reconstruction. Both cases involved autologous tissue reconstruction. Although external nasal morphology improved in both cases, long-term follow-up revealed contracture and secondary deformity, suggesting that outcomes were not entirely satisfactory. Accurate assessment of the remaining nasal components-including soft tissue and skeletal framework-is critical for selecting an appropriate reconstructive strategy.

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