Case Report: Uncommon co-occurrence of different renal histopathological entities in a patient with multiple myeloma and lymphoplasmacytic lymphoma

病例报告:多发性骨髓瘤和淋巴浆细胞淋巴瘤患者罕见的肾脏组织病理学异常同时发生

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Abstract

In patients with plasma cell dyscrasias presenting with kidney injury, renal biopsy usually displays the presence of a single histological damage. However, the coexistence of heterogeneous damages has been occasionally described and is associated with worse renal outcomes. In this report, we describe the case of a patient with a concomitant diagnosis of multiple myeloma and lymphoplasmacytic lymphoma, presenting with acute kidney injury and with renal biopsy revealing the unexpected concurrent presence of several different renal damages, who achieved a good hematologic response and dialysis independence after anti-myeloma therapy.

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