Abstract
The Coronavirus Disease 2019 (COVID-19) pandemic prompted global universities to adopt online teaching, yet limited research exists on its efficacy in morphology experiments. This study evaluates online versus offline teaching outcomes in histology and pathology courses during 2020 to 2023. We implemented hybrid (asynchronous/synchronous) online morphology experiments and compared results with historical offline face-to-face teaching. Outcomes were assessed through lab reports, mid-term/final exams, and a validated satisfaction survey (5-point Likert scale). Among 855 participants (446 online, 409 offline), 55.83% preferred offline teaching for enhanced interaction (P < .01), though online learners reported comparable satisfaction (4.25 ± 0.64 vs 4.38 ± 0.84, P = .157). Online groups scored lower in lab reports (19.37 ± 1.50 vs 19.63 ± 1.39, P < .001) and mid-terms (25.83 ± 3.41 vs 27.54 ± 3.07, P < .001), but achieved parity in finals (39.43 ± 8.63 vs 40.57 ± 7.51, P = .112). All of these results differed in different grades, genders or specialties. The online teaching mode of morphology experiments produces comparable teaching effects, especially during the COVID-19 epidemic. It also provides additional experience, new perspectives, and new ideas for offline teaching. It indicated combining online flexibility with in-person engagement could enhance future teaching outcomes.