Abstract
The novel coronavirus disease (COVID-19), which appeared in Wuhan, China, is spreading rapidly worldwide. Health systems in many countries have collapsed as a result of this pandemic, and hundreds of thousands of people have died due to acute respiratory distress syndrome caused by this virus. As a result, diagnosing COVID-19 in the early stages of infection is critical in the fight against the disease because it saves the patient's life and prevents the disease from spreading. In this study, we proposed a novel approach based on transfer learning and deep support vector data description (DSVDD) to distinguish among COVID-19, non-COVID-19 pneumonia, and intact CT images. Our approach consists of three models, each of which can classify one specific category as normal and the other as anomalous. To our knowledge, this is the first study to use the one-class DSVDD and transfer learning to diagnose lung disease. For the proposed approach, we used two scenarios: one with pretrained VGG16 and one with ResNet50. The proposed models were trained using data gathered with the assistance of an expert radiologist from three internet-accessible sources in end-to-end fusion using three split data ratios. Based on training with 70%, 50%, and 30% of the data, the proposed VGG16 models achieved (0.8281, 0.9170, and 0.9294) for the F1 score, while the proposed ResNet50 models achieved (0.9109, 0.9188, and 0.9333).