Smcr8 deficiency disrupts axonal transport-dependent lysosomal function and promotes axonal swellings and gain of toxicity in C9ALS/FTD mouse models

Smcr8 缺陷会破坏轴突运输依赖性溶酶体功能，并促进 C9ALS/FTD 小鼠模型中的轴突肿胀和毒性增加。