Abstract
In his poetry, Walt Whitman sings, "I am large, I contain multitudes." Most healthy organisms are made up of a multitude of cells and cell types, but none of these cells acts alone. Likewise a cell in homeostasis contains many organelles, but none of these organelles work on their own. How these diverse cells and how these different organelles communicate with each other in time and space are scientific questions that intrigue me. At the same time, like these cooperating cells and organelles, my research is constantly reshaped and transformed by interacting with different people, from my encouraging mentors, energetic trainees, and inspiring colleagues. These personal collaborations motivate and advance my research toward understanding cellular communications that promote metabolic health and organism longevity.