Abstract
INTRODUCTION: Given the accessibility of community pharmacists as the first point of care in Nigeria and their expanding role in optimizing public health, it is critical that they employ evidence-based, ethical practices. This study assessed ethical practices and identified drivers of unethical practices among community pharmacists in Nigeria. METHODS: A convergent-parallel mixed method study design was employed, collecting quantitative and qualitative data, which were analyzed using SPSS and inductive content analysis. RESULTS: Most pharmacists maintained patients' confidentiality (93.2%), and disclosed side effects of medicines to patients (80.3%). Nearly half (48.9%) dispensed antibiotics without prescriptions and more than one-third purchased medicines from the unregulated open market (38.4%). Conversely, only 53.4% performed quality checks to identify possible or suspected substandard and falsified medicines. Pharmacists who regularly consulted the PCN code of ethics were less likely to dispense antibiotics without prescriptions (p = 0.011), stock medicines not approved by NAFDAC (p = 0.010), or purchase from open markets (p = 0.027). Key drivers of unethical pharmacy practices include poor physician-pharmacist interprofessional collaboration (76.3%), patient pressure (73.9%), and managerial pressure to meet sales targets (70.3%). Qualitative responses highlighted competitive pressure, expressed as fear of losing clients, poor working conditions, poor regulation, and unethical, profit-driven, managerial practices as drivers of unethical pharmacy practices. Potential limitations to this study include recall bias and the Hawthorne effect. CONCLUSION: Pharmacists' unethical practices potentially contribute to the prevalence of substandard and falsified medicines, and antimicrobial resistance. Improved regulations, improved remuneration, providing incentives for professionalism, training on ethics and improved multidisciplinary collaborations could promote ethical community pharmacy practices.