Abstract
OBJECTIVES: Empty nose syndrome (ENS) is a rare postoperative complication that can develop following turbinate surgery. Here, we present our clinical experience and a comprehensive analysis of the inferior meatus augmentation procedure with autologous costal cartilage (IMAP-ACC) as a treatment for ENS. METHODS: We retrospectively reviewed the medical records of patients diagnosed with ENS who underwent IMAP-ACC at a tertiary referral center between November 2015 and November 2023. Symptom improvement was evaluated using the Empty Nose Syndrome 6-Item Questionnaire (ENS6Q) score before and after the procedure. In addition, perioperative complications and instances of revision surgery were systematically examined. RESULTS: Of the 32 patients who underwent IMAP-ACC, clinical analysis included 20 patients (16 men, 4 women) with a mean age of 39.1±11.5 years and a mean follow-up duration of 61.2±28.8 months. The mean ENS6Q score significantly improved from 17.5±5.3 preoperatively to 9.1±6.0 at the final follow-up (P<0.001). In a subgroup analysis of 16 patients with available early follow-up data, significant reductions in ENS6Q scores were observed both at early follow-up (7.8±5.7) and long-term follow-up (8.6±6.5), compared to the preoperative value (18.2±5.6). Across all 32 patients, nasal obstruction was the most common perioperative complication (34.4%), necessitating reoperation in four patients (12.5%). The majority of complications were effectively managed with a conservative approach. CONCLUSION: IMAP-ACC has proven to be a valuable and durable treatment option for patients with ENS, demonstrating sustained symptom improvement over extended follow-up periods.