Abstract
For the first time in human history, hundreds of millions of people all over the world have been subjected to compulsory vaccination with a new type of nucleic acid based vaccines in order to keep their jobs or be able to travel due to some notorious coronavirus disease 2019 (COVID-19) mandates. The vast majority of African countries were either initially deprived of these vaccines, or later, a majority of the population was too skeptical to receive them and preferred a safe early treatment pharmacological approach. Yet, Africa had the lowest COVID-19 mortality rate compared to those countries that adopted mass vaccination. This letter to the editor adds African insights that should be helpful in future pandemics to save millions of precious lives.