Abstract
The brain is a biological system comprising nerve cells and orchestrates its embodied agent's perception, behavior, and learning in dynamic environments. The free-energy principle (FEP) advocated by Karl Friston explicates the local, recurrent, and self-supervised cognitive dynamics of the brain's higher-order functions. In this study, we continue to refine the FEP through a physics-guided formulation; specifically, we apply our theory to synaptic learning by considering it an inference problem under the FEP and derive the governing equations, called Bayesian mechanics. Our study uncovers how the brain infers weight changes and postsynaptic activity, conditioned on the presynaptic input, by deploying generative models of the likelihood and prior belief. Consequently, we exemplify the synaptic efficacy in the brain with a simple model; in particular, we illustrate that the brain organizes an optimal trajectory in neural phase space during synaptic learning in continuous time, which variationally minimizes synaptic surprisal.