Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function

摇动技术形成的大鼠肝细胞球体保持分化的肝细胞基因表达和功能

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作者:Colleen M Brophy, Jennifer L Luebke-Wheeler, Bruce P Amiot, Harris Khan, Rory P Remmel, Piero Rinaldo, Scott L Nyberg

Conclusion

Spheroid formation by rocker technique was more rapid and more efficient than by rotational technique. Rocker-formed spheroids appear suitable for application in a bioartificial liver or as an in vitro liver tissue construct.

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