Recovery and detection of botulinum neurotoxins from a nonporous surface

从非多孔表面回收和检测肉毒杆菌神经毒素

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Abstract

We describe the adaptation of a sample recovery method for botulinum neurotoxins from stainless steel. Botulinum toxin was recovered from surfaces left to dry for up to 16 h and detected by either ELISA or EndoPep mass spectrometry methods. In addition, we demonstrate that this method can be used to evaluate the efficacy of surface decontamination procedures.

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