5-azacytidine in chronic myelomonocytic leukemia: case report and review of literature

5-氮杂胞苷治疗慢性粒单核细胞白血病:病例报告及文献综述

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Abstract

Hypomethylating drugs are useful in the management of Myelodysplastic syndromes, but there are only few reports on chronic myelomonocycitic (CMML) leukemia patients. We describe our experience in 3 CMML patients treated with azacitidine. Two patients obtained partial response after 4 treatment cycles with only minor toxicity and are in continuous partial response, with stable peripheral blood counts, at 29 and 30 cycles from treatment start.

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