Abstract
Accidental arterial puncture is a rare but significant complication associated with central venous catheterization. This report describes a case of inadvertent subclavian artery catheterization that was successfully managed with the ExoSeal vascular closure device. A female patient in her early 30s was hospitalized for severe acute pancreatitis that necessitated cannulation of the right subclavian vein. Postprocedure, infusion difficulties suggested a need for arterial catheterization, which was confirmed by imaging. The intervention resulted in prompt hemostasis and prevented further vascular injury, resulting in complication-free recovery. This case highlights the importance of rapid identification and treatment of arterial injury during central venous catheterization, and also demonstrates the effectiveness of ExoSeal in the management of vascular complications, especially in high-risk conditions.