Abstract
The COVID-19 pandemic has come to stay, at least for a while. The initial bewilderment and restrictive measures have given way to the population's mental decay and increased stress on workers facing work and family demands in a difficult-to-manage situation. For this reason, this descriptive cross-sectional study sought to analyze stress levels in a sample of 263 general and healthcare workers (from 24 to 67 years of age) and their relationship with negative work-home interaction (WHI) and with gender in the second wave of contagions and deaths caused by the COVID-19 pandemic in Spain (October-December 2020). The results showed that having a higher level of WHI, the presence of work overload, health concerns, economic concerns, and lower-income were predictors of stress among these workers. Age and health-related occupations were contributing factors to work overload and health-related concerns. In addition, the relationship between being a woman and suffering from higher stress levels was mediated by income level, economic concern, and the WHI. Other variables such as having children or dependents, marital status, concern for the health of others, and teleworking were not associated with the stress levels detected in the sample. This research pays attention to the health state of workers beyond the initial stage of the pandemic, where most studies on this issue have concentrated. Thus, this study provides evidence of the uneven impact this crisis has on women and men, contributing to clarifying the relationship between gender, the WHI, and stress.