Abstract
Healthy older adults commonly report increased difficulties with language production. This could reflect decline in the language network, or age-related declines in other cognitive abilities that support language production, such as executive function. To examine this possibility, we conducted a whole-brain resting-state functional connectivity (RSFC) analysis in older and younger adults using two seed regions-the left posterior superior temporal gyrus and left inferior frontal gyrus. Whole-brain connectivities were then correlated with Stroop task performance to investigate the relationship between RSFC and executive function. We found that overall, younger adults had stronger RSFC than older adults. Moreover, in older, but not younger, adults stronger RSFC between left IFG and right hemisphere executive function regions correlated with better Stroop performance. This suggests that stronger RSFC among older adults between left IFG and right hemisphere regions may serve a compensatory function.