Impact of Needle-Free Connector and Prefilled Flushing Syringe Shortage on CLABSI Rates in Pediatric Intensive Care

无针连接器和预充式冲洗注射器短缺对儿科重症监护室中心静脉导管相关血流感染率的影响

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Abstract

OBJECTIVE: We aimed to discuss our experience of a higher incidence of catheter-associated bloodstream infections (CLABSIs) during the needle-free connector (NFC) and single-use prefilled flushing syringe (PFS) shortage. MATERIALS AND METHODS: Retrospective analyses were carried out to investigate the CLABSI rates at a tertiary training hospital from January 1, 2023, to December 31, 2023, and the study period included a three-month shortage of NFCs and PFSs in April and June 2023. RESULTS: The CLABSI rate for the three months was 5.94 per 1000 CL days from January 1 to March 31, 18.07 per 1000 CL days from April 1 to June 30, 5.42 per 1000 CL days from July 1 to September 30, and 6.52 per 1000 CL days from October 1 to December 31. Following the three-month shortage period, the rate of CLABSI significantly increased from 5.94 per 1000 CL days to 18.07 per 1000 CL days. After the shortage of needle-free connectors and single-use PFSs was resolved, the rate of CLABSI significantly decreased to 5.42 per 1000 CL days (p<0.001). CONCLUSION: Even a three-month lack of NFC and PFS caused three-fold CLABSI. The efficacy and ongoing success of CLABSI prevention depend on maintaining the materials' continuity.

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