Sugar and spice: Fc glycosylation in antibody-mediated transplant rejection

糖和香料:抗体介导的移植排斥反应中的Fc糖基化

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Abstract

Bharadwaj et al.(1) demonstrate that anti-donor HLA antibodies display low levels of Fc fucosylation. This signature was associated with potent provocation of NK cell effector functions and was discriminative for active antibody-mediated rejection among patients with donor specific HLA antibodies.

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