Abstract
PURPOSE: The aim of this study is to compare the periodontal status and quantify Porphyromonas gingivalis (Pg) and Prevotella intermedia (Pi) from plaque samples of both gestational diabetic mellitus (GDM) and non diabetic pregnant women. MATERIALS AND METHODS: Sixty first time pregnant women were selected after adjusting for age, duration of pregnancy and educational status. They were then categorized into gestational diabetic women (GDM) (Group A) and healthy pregnant women (non GDM) (Group B). Periodontal examination was done by assessing gingival index, periodontal disease index and probing depth. Microbial analysis on sub-gingival plaque was performed using polymerase chain reaction (PCR). Statistical analysis was done by student t test, chi square test and Fischer exact test. RESULTS: Group A showed higher gingival index, probing depth and periodontal disease index scores than group B at p < 0.001. Pg was detected in 80% of group A and 40% of group B. Amongst these; it was measured over 2.0 × 10(4) in 33% of group A, while in the group B it never scored more than 1.0 × 10(4). While Pi were also detected in 73% of group A women and 40% Group B women but quantification showed Pi > 2.0 × 10(4) in more number of group A women. CONCLUSION: This study showed that there is significant association between the severity of periodontal disease and increased levels of Pg and Pi in gestational diabetic women.