Comment on Gustavson syndrome is caused by an in-frame deletion in RBMX associated with potentially disturbed SH3 domain interactions

关于古斯塔夫森综合征的评论指出,该综合征是由RBMX基因的框内缺失引起的,并可能伴有SH3结构域相互作用的紊乱。

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Abstract

Johansson et al. recently described the genetic diagnosis of a large family with Gusatvson syndrome. The pathogenic variant in this family is an in-frame deletion in RBMX, also known as HNRNPG. This work expands the definition of the HNRNP-Related Neurodevelopmental Disorders and provides insights into analyzing the related conditions.

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