An association analysis to identify genetic variants linked to asthma and rhino-conjunctivitis in a cohort of Sicilian children

一项关联分析旨在识别西西里儿童队列中与哮喘和鼻结膜炎相关的遗传变异

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Abstract

Asthma and rhino-conjunctivitis are common chronic diseases in childhood. In this cross-sectional study, we performed a gene association analysis with current asthma and rhino-conjunctivitis in a cohort of Sicilian children aged 10-15 years. Overall, our findings reveal the importance of different genetic variants at 4p14, 16p12.1, 17q12, 6p12.2 and 17q21.1, identifying possible candidate genes responsible for susceptibility to asthma and rhino-conjunctivitis.

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