Abstract
Systemic Lupus erythematosus is the classic prototype of multisystem disease of autoimmune origin. SLE may be associated Vasculitis as an overlap syndrome. In this paper, a patient diagnosed as SLE with Vasculitis, which was managed successfully by Ayurveda treatment was discussed. A 39-year-old female patient came to hospital with complaint of severe pain and burning sensation in both the legs for two months, associated with ulceration and gangrene of toes of both the legs for the last 15 days. She was diagnosed as SLE overlap vasculitis from a higher medical centre with relevant investigations and advised to go for amputation. As patient was not willing for surgery, alternatively opted for Ayurveda treatment. The condition was diagnosed as disease Vatarakta according to Ayurveda and treatment was planned accordingly. Treatment was planned by selecting suitable oral medicines, suitable panchakarma procedures along with the ulcer management. Tinospora cordifolia was the main drug of choice. Treatment was successful and able to save the limb. Patient was followed up for more than a year without any complications and relapses.