From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition

从假ceRNA到环状ceRNA:一段关于相互作用和竞争的故事

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Abstract

RNA is believed to have been the first reservoir of genetic information, but despite its ancient history, RNA continues to fascinate and is only now beginning to be understood in its entire variety and communication modality. New discoveries include the pseudogene RNA network regulating PTEN transcription and translation and the identification of circular RNAs as a new class of competing endogenous RNA molecules that sequester microRNAs to suppress their function.

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