Abstract
OBJECTIVE: This paper discussed the dredging effect and safety of ethylenediaminetetraacetic acid (EDTA) combined with C-pilot files and microultrasound (mUS) on root canal calcification. METHODS: From October 2021 to January 2022, 132 patients with calcified root canals treated in our hospital were selected as the research subjects. Among them, 64 cases who received EDTA combined with C-pilot Files and mUS plus ultrasonic instruments to dredge calcified root canals were regarded as the research group (RG), and another 68 cases given ultrasonic instruments plus C-pilot files were regarded as the control group (CG). The root canal dredging time was recorded, and the dredging success rate and total success rate of different tooth positions and calcification sites were compared between groups. The clinical efficacy was assessed 6 months after treatment. Pain severity was evaluated by the Pain Intensity Numerical Rating Scale (PI-NRS) before (T0), during (T1), and after treatment (T2). Finally, the incidence of adverse reactions within one week after treatment was counted. RESULTS: RG was observed with statistically higher success rates of root canal dredging in different tooth positions and calcified sites than CG (P < 0.05). Besides, the total effective rate of treatment was 92.19% in RG, which was also higher compared with CG, while the root canal dredging time in RG was shorter than that in CG (P < 0.05). Increased NRS scores were found in both groups at T1, and the score in RG was significantly lower compared with that in CG. At T2, both groups showed a lower PI-NRS score than T1 but higher than T0, and the score at T2 was also lower in RG as compared to CG (P < 0.05). Moreover, the reduced incidence of adverse reactions were observed in RG compared with CG (P < 0.05). CONCLUSIONS: EDTA combined with C-pilot files and mUS can effectively improve the dredging success rate of root canals obstructed by calcification, shorten the dredging time, and improve patient comfort, which is an effective method for clinical dredging of calcification obstructed root canals.