Abstract
BACKGROUND: It is currently accepted that sign languages and spoken languages have significant processing commonalities. The evidence supporting this often merely investigates frontotemporal pathways, perisylvian language areas, hemispheric lateralization, and event-related potentials in typical settings. However, recent evidence has explored beyond this and uncovered numerous modality-dependent processing differences between sign languages and spoken languages by accounting for confounds that previously invalidated processing comparisons and by delving into the specific conditions in which they arise. However, these processing differences are often shallowly dismissed as unspecific to language. SUMMARY: This review examined recent neuroscientific evidence for processing differences between sign and spoken language modalities and the arguments against these differences' importance. Key distinctions exist in the topography of the left anterior negativity (LAN) and with modulations of event-related potential (ERP) components like the N400. There is also differential activation of typical spoken language processing areas, such as the conditional role of the temporal areas in sign language (SL) processing. Importantly, sign language processing uniquely recruits parietal areas for processing phonology and syntax and requires the mapping of spatial information to internal representations. Additionally, modality-specific feedback mechanisms distinctively involve proprioceptive post-output monitoring in sign languages, contrary to spoken languages' auditory and visual feedback mechanisms. The only study to find ERP differences post-production revealed earlier lexical access in sign than spoken languages. Themes of temporality, the validity of an analogous anatomical mechanisms viewpoint, and the comprehensiveness of current language models were also discussed to suggest improvements for future research. KEY MESSAGE: Current neuroscience evidence suggests various ways in which processing differs between sign and spoken language modalities that extend beyond simple differences between languages. Consideration and further exploration of these differences will be integral in developing a more comprehensive view of language in the brain.