Abstract
OBJECTIVE: To compare body composition parameters estimated by air displacement plethysmography (ADP) to dual X-ray absorptiometry (DXA) in body mass index (BMI) classifications that include extremely obese (BMI ≥ 40.0 kg/m(2) ), and to examine if differences between analyses were influenced by BMI. METHODS: Fat-free mass (FFM, kg), fat mass (FM, kg), and body fat (BF, %) were analyzed with both technologies. RESULTS: All outcome measures of ADP and DXA were highly correlated (r ≥ 0.95, P < 0.001 for FFM, FM, and BF), but Bland-Altman analyses revealed significant bias (P < 0.01 for all). ADP estimated greater FFM and lower FM and BF (P < 0.01 for all). BMI explained 27% of the variance in differences between FFM measurements (P < 0.001), and 37 and 33% of the variances in differences between FM and BF measurements, respectively (P < 0.001 for both). Within normal weight and overweight classifications, ADP estimated greater FFM and lower FM and BF (P < 0.001 for all), but the opposite occurred within the extremely obese classification; ADP estimated lower FFM and greater FM and BF (P < 0.05 for all). CONCLUSIONS: Body composition analyses by the two technologies were strongly congruent, but systematically different and influenced by BMI. Caution should be taken when utilizing ADP to estimate body composition parameters over a wide range of BMI classifications that include extremely obese.