Abstract
Any disease that spreads quickly and crossed the geographical barrier is termed as pandemic. After the initial occurrence of Covid-19 from China, World Health Organization had declared novel corona viral outbreak as pandemic on March, 2020. Since then, COVID-19 continued to devastate people all around the world. Human civilization has witnessed one of its greatest crises by facing 180 million of confirmed cases with 38.9 lakh deaths across the world till end of June 2021. India alone contributes 30 million of positive cases and has lost 3.92 lakh valuable lives (data as on 24(th) of June 2021 from CSSEGIS and Data (http://github.com/CSSEGISandData/COVID-19); (the number increases in each day). Bio-medical experts from all around the world are working tirelessly to limit the disease and find potential cures for this viral infection. Vaccination is the most effective strategy to prevent the spread of any viral disease. Virologists have developed some effective vaccines, but production or supply lags far behind the present demand across the globe. Plant-derived vaccines (PDVs) based on modified virus like particles (VLPs) can be a feasible alternative in this case. A summarized account about the efficacy of the first plant-derived Covid 19 vaccine, CoVLP is discussed. PDVs and VLPs are also reviewed briefly, along with their benefits and drawbacks.