Hepatocellular adenoma with activation of the β-catenin mutation pathway mimicking intrahepatic cholangiocarcinoma: Case report

肝细胞腺瘤伴β-catenin突变通路激活,临床表现酷似肝内胆管癌:病例报告

阅读:2

Abstract

Hepatocellular adenomas are relatively rare benign tumors of the liver that primarily develop in young women, particularly those who use oral contraceptive pills. There are 4 distinct subtypes of these tumors. Among them, β-catenin-mutated adenomas constitute approximately 10% to 15% and are notable for their potential to undergo malignant transformation. In this report, we present the case of a young patient who had a 4 cm hepatic lesion. The initial imaging studies, particularly an MRI, suggested that the lesion might be an intrahepatic cholangiocarcinoma. However, upon further histological examination, the lesion was identified as a benign hepatic adenoma, with activation of the β-catenin mutation pathway. Due to the associated risk of malignant transformation, the treatment plan included surgical resection of the adenoma. This approach is critical in managing such lesions to prevent any potential progression to hepatocellular carcinoma.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。