The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis

大麻素受体 CB1 有助于子宫内膜异位症小鼠模型中异位病变的发展

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作者:Ana-Maria Sanchez, Federica Quattrone, Maria Pannese, Adele Ulisse, Massimo Candiani, Javier Diaz-Alonso, Guillermo Velasco, Paola Panina-Bordignon

Methods

Endometriosis-like lesions were induced in Balb/c and C57/Bl6 mice. Two weeks after disease induction, the lesions were counted, measured and either included for immunohistochemistry analysis or frozen for gene expression profiling by semi-quantitative real-time PCR. To limit the role of chance, the experiments were conducted under standardized laboratory conditions with appropriate controls. Main

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