The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis
大麻素受体 CB1 有助于子宫内膜异位症小鼠模型中异位病变的发展
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作者:Ana-Maria Sanchez, Federica Quattrone, Maria Pannese, Adele Ulisse, Massimo Candiani, Javier Diaz-Alonso, Guillermo Velasco, Paola Panina-Bordignon
| 期刊: | Human Reproduction | 影响因子: | 6.000 |
| 时间: | 2017 | 起止号: | 2017 Jan;32(1):175-184. |
| doi: | 10.1093/humrep/dew281 | 种属: | Mouse |
| 研究方向: | 信号转导 | |
Methods
Endometriosis-like lesions were induced in Balb/c and C57/Bl6 mice. Two weeks after disease induction, the lesions were counted, measured and either included for immunohistochemistry analysis or frozen for gene expression profiling by semi-quantitative real-time PCR. To limit the role of chance, the experiments were conducted under standardized laboratory conditions with appropriate controls. Main
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