Abstract
Identifying and managing the most critical side effects encourages patients to take medications regularly and adhere to the course of treatment. Therefore, priority should be given to the more important ones, among these side effects. However, the number of studies that make a priority examination is limited. There is a need for a new study that determines which of these effects are more priority to increase the quality of the treatment. Accordingly, this study aims to define the most important side effects of antidepressant drugs with a novel model. Quantum Spherical fuzzy M-SWARA technique is considered to compute the importance weights of the items. The main contribution of this study is that the most critical side effects can be understood for antidepressant drugs by establishing a novel decision-making model. The findings demonstrate that psychological side effects are defined as the most critical side effects of antidepressant drugs. Furthermore, physical side effects also play a key role in this condition. Side effects in antidepressant treatment have a great impact on the effectiveness of treatment and patient compliance.