Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism

他汀类药物诱发横纹肌溶解症,发生于肾功能衰竭合并未确诊甲状腺功能减退症的患者

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Abstract

Rhabdomyolysis is a syndrome characterized by muscle necrosis which causes the release of myoglobin into the bloodstream. The manifestations of this syndrome range from asymptomatic elevation of serum muscle enzymes to life-threatening cases associated with extremely high enzyme levels, electrolyte imbalance, and acute renal failure. Symptoms of rhabdomyolysis include dark urine, muscle weakness, and fatigue. Statins are commonly used drugs for the prevention and management of dyslipidemia. We present an interesting and critical case on statin-induced rhabdomyolysis with renal failure and previously undiagnosed idiopathic hypothyroidism.

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