Abstract
PURPOSE: To report the off-label use of the SING IMT telescopic intraocular lens (IOL) (Samsara Vision) in a patient with inverse retinitis pigmentosa (RP) and cataracts, evaluating its impact on visual acuity and functional outcomes. OBSERVATIONS: A 77-year-old female with inverse RP, bilateral cataracts, hypertension, and hypercholesterolemia presented with hand motion visual acuity (≥2.3 LogMAR) bilaterally, assessed using the Early Treatment Diabetic Retinopathy Study (ETDRS) chart at 2 meters. An external telescopic simulator improved visual acuity to 6 letters (1.58 LogMAR) in the left eye. Preoperative assessments, including optical coherence tomography, fundus autofluorescence, and electrophysiological testing, confirmed central macular degeneration and supported left-eye SING IMT implantation. Phacoemulsification with SING IMT implantation was performed, followed by a visual rehabilitation program. By 6 months, visual acuity reached 6 ETDRS letters (1.58 LogMAR) at 3 meters. Functional improvements included reading, writing, sewing, and television viewing, with enhanced autonomy and mood. Mild corneal edema resolved within 1 week, and no posterior capsular opacification or cystoid macular edema occurred during 8 months of follow-up. CONCLUSION AND IMPORTANCE: This case reporting use of the SING IMT in inverse RP demonstrates its potential to improve vision and quality of life in patients with central vision loss from retinal dystrophies, surpassing typical cataract surgery outcomes. The 2.5x magnification and structured rehabilitation were key to functional gains. Larger studies are needed to validate efficacy and refine patient selection.