Abstract
PURPOSE: To report a case of rapid neuroadaptation to surgically-induced aniseikonia in a 17-year-old with preoperative anisometropia of 9.5 D. OBSERVATIONS: A 17-year-old female with a history of retinopathy of prematurity (ROP) and progressive high myopia with resulting anisometropia secondary to conventional laser photocoagulation in her right eye was found to have diplopia after undergoing cataract surgery in that eye. Other etiologies of diplopia were ruled out and reversal of anisometropia remained the only viable diagnosis. Her diplopia fully resolved without intervention within one month of the surgery. CONCLUSION AND IMPORTANCE: In cases of neuroadaptation to long standing anisometropia, even if that anisometropia develops in infancy, abrupt reversal following surgery can be surprisingly well tolerated.