Real-time and non-invasive monitoring of embryonic stem cell survival during the development of embryoid bodies with smart nanosensor

利用智能纳米传感器实时无创监测胚状体发育过程中胚胎干细胞的存活情况

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作者:Jiayin Fu, Christian Wiraja, Ruiqi Chong, Chenjie Xu, Dong-An Wang

Significance

The distribution pattern of viable embryonic stem cells (ESCs) within embryoid body (EB) is closely related with the maturation of EBs. Noninvasive and real-time monitoring of viable ESC distribution in EBs would allow researchers to optimize the culturing condition in time during the EB development and to select the suitable EBs for subsequent applications.

Statement of significance

The distribution pattern of viable embryonic stem cells (ESCs) within embryoid body (EB) is closely related with the maturation of EBs. Noninvasive and real-time monitoring of viable ESC distribution in EBs would allow researchers to optimize the culturing condition in time during the EB development and to select the suitable EBs for subsequent applications.

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