Centrosomes tune in to metabolic state and turn on to oxygen

中心体根据代谢状态进行调节并开启氧气通道。

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Abstract

Events required for cell-cycle progression, including centriole duplication and mitotic spindle formation, are obligatorily linked to the metabolic state of a cell. In this issue of Developmental Cell, Moser et al. (2013) show that PHD1 can act as such a sensor through proline hydroxylation of the centrosomal protein Cep192.

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