A close look at wiggly chromosomes

仔细观察弯曲的染色体

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Abstract

In a recent issue of Cell, Fisher et al. (2013) use high-resolution time-lapse imaging to peer into bacterial genome (nucleoid) structure. The nucleoid, an elastic filament confined via an internal network, undergoes periodic fluctuations critical in relieving tension. Programmed tethers and their release highlight a primordial mechanical cycle for chromosome segregation.

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