Association between higher plasma lutein, zeaxanthin, and vitamin C concentrations and longer telomere length: results of the Austrian Stroke Prevention Study

血浆叶黄素、玉米黄质和维生素 C 浓度较高与端粒长度较长之间的关联:奥地利中风预防研究的结果

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作者:Abhijit Sen, Gunther Marsche, Paul Freudenberger, Michael Schallert, Anna M Toeglhofer, Christoph Nagl, Reinhold Schmidt, Lenore J Launer, Helena Schmidt

Conclusion

This study provides first evidence that higher lutein, zeaxanthin, and vitamin C concentrations in plasma are associated with longer LTL in normal elderly persons and suggest a protective role of these vitamins in telomere maintenance.

Results

Multiple linear regression analyses with adjustment for age and sex demonstrated that higher lutein, zeaxanthin, and vitamin C concentrations were strongly associated with longer telomere length. The associations were independent of body mass index, maximum oxygen uptake, and vascular risk factors and were not mediated by advanced oxidation protein products content.

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