Human vaccines & immunotherapeutics: News November 2022

人类疫苗和免疫疗法:2022年11月新闻

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Abstract

Limited data are available regarding the seroprevalence of measles, mumps, rubella, and varicella (MMRV) among emergency medical technicians (EMTs) in Japan. The present study aimed to review a project to evaluate adequate immunity against MMRV for the requirement of additional vaccination among EMTs in accordance with the Japanese Society for Infection Prevention and Control guidelines. A retrospective observational study was conducted as part of a vaccination program for EMTs. Each participant was evaluated for medical history, vaccination history, and serology using the criteria established by the Japanese Society of Infection Prevention and Control. In total, 85 EMTs (median age, 31 years; male, 92.9%) were included. Among the included EMTs, 32 (37.6%), 54 (63.5%), 46 (54.1%), and 84 (98.9%) were seropositive for measles, rubella, mumps, and varicella, respectively, whereas 1 (1.2%), 6 (7.1%), 5 (5.9%), and 0 (0%) were seronegative. Furthermore, 48 (56.5%), 27 (31.8%), 45 (52.9%), and 8 (9.4%) EMTs received an additional dose of vaccines for measles, rubella, mumps, and varicella, respectively. The present study suggests that EMTs are not fully immune to MMRV, which highlights the need for confirming the immune status and additional vaccination requirement to prevent occupational infections.

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