Abstract
The effect of COVID-19 is enormous, and high-risk COVID-19 case arises when underlying infections like diabetes, chronic obstructive pulmonary disease, heart failure, coronary artery disease, or cardiomyopathy are present, and an immunocompromised state such as Human Immunodeficiency Virus (HIV). People living with HIV(PLHIV) may be exposed to severe COVID-19, mostly in areas with poor access to proper care and complex intervention for HIV infection. During the lockdown, those with medical appointments will not access health facilities, which may be detrimental to people living with HIV. Emerging evidence suggests COVID-19 pandemic fear may lead to adverse mental health outcomes and affect preventive behavior. In addition to the stigma and discrimination associated with HIV, COVID-19 is also causing concerns. People with HIV tend to have mental health issues such as depression, anxiety, and post-traumatic stress (PTSD), which can be both a cause and a harmful impact of HIV. Discussed in this research is the effect of the COVID-19 pandemic on HIV patients, their similarities, differences, and urgent attention from healthcare centers to take charge and respond to patients with HIV and other immunosuppressed conditions during the COVID-19 pandemic.