Generalizability of randomized trial results to target populations: Design and analysis possibilities

随机试验结果对目标人群的普遍适用性:设计和分析的可能性

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Abstract

Randomized trials play an important role in estimating the effect of a policy or social work program in a given population. While most trial designs benefit from strong internal validity, they often lack external validity, or generalizability, to the target population of interest. In other words, one can obtain an unbiased estimate of the study sample average treatment effect (SATE) from a randomized trial; however, this estimate may not equal the target population average treatment effect (TATE) if the study sample is not fully representative of the target population. This paper provides an overview of existing strategies to assess and improve upon the generalizability of randomized trials, both through statistical methods and study design, as well as recommendations on how to implement these ideas in social work research.

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