Norovirus Antigen Detection with a Combination of Monoclonal and Single-Chain Antibodies

利用单克隆抗体和单链抗体联合检测诺如病毒抗原

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Abstract

The performance of a norovirus antigen detection assay was assessed using monoclonal antibody NV23 and single-chain antibody HJT-R3-A9 to identify both virus-like particles and virus-containing fecal samples. The detection of 25 different norovirus genotypes as recombinant virus-like particles or in clinical samples was dependent on virus or antigen concentration.

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