Implementation of a Consensus Set of Hypervariable Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Loci in Mycobacterium tuberculosis Molecular Epidemiology

结核分枝杆菌分子流行病学中高变型散在重复单元可变数目串联重复序列位点共识集的实施

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作者：Trovato,Alberto,Tafaj,Silva,Battaglia,Simone,Alagna,Riccardo,Bardhi,Donika,Kapisyzi,Perlat,Bala,Silvana,Haldeda,Migena,Borroni,Emanuele,Hafizi,Hasan,Cirillo,Daniela Maria
期刊：Journal of Clinical Microbiology影响因子：5.400
时间：2016起止号：2016 Feb;54(2):478-82
doi：10.1128/JCM.02945-15

Abstract

This study shows that the addition of a consensus 4-locus set of hypervariable mycobacterial interspersed repetitive-unit-variable-number tandem repeat (MIRU-VNTR) loci to the spoligotyping-24-locus MIRU-VNTR typing strategy is a well-standardized approach that can contribute to an improvement of the true cluster definition while retaining high typeability in non-Beijing strains.

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