Whole-genome sequencing of Burkholderia pseudomallei isolates from an unusual melioidosis case identifies a polyclonal infection with the same multilocus sequence type

对一例罕见类鼻疽病例中分离出的伯克霍尔德氏菌进行全基因组测序,发现其为具有相同多位点序列分型的多克隆感染。

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Abstract

Twelve Burkholderia pseudomallei isolates collected over a 32-month period from a patient with chronic melioidosis demonstrated identical multilocus sequence types (STs). However, whole-genome sequencing suggests a polyclonal infection. This study is the first to report a mixed infection with the same ST.

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