Buruli ulcer disease in travelers and differentiation of Mycobacterium ulcerans strains from northern Australia

旅行者布鲁里溃疡病及澳大利亚北部溃疡分枝杆菌菌株的鉴别

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Abstract

Buruli ulcer (BU) is a necrotizing infection of skin and soft tissue caused by Mycobacterium ulcerans. In Australia, most cases of BU are linked to temperate, coastal Victoria and tropical, northern Queensland, and strains from these regions are distinguishable by variable-number tandem repeat (VNTR) typing. We present an epidemiological investigation of five patients found to have been infected during interstate travel and describe two nucleotide polymorphisms that differentiate M. ulcerans strains from northern Australia.

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